Patient no. | Agea/Sex | FABb,c | Disease statusd | Cytogeneticse | Cytogenetics risk group at relapse | Remission duration (months)f | Previous treatments | GO reinduction | |||
Remission inductiong,h,i | Consolidation j,k | ||||||||||
1 | 65/M | M6 | Non-CR | complex karyotype | Unfavorable | * | IDA + AraC | - | AraC 2000 mg/m2 on days 1 - 5 | +MIT 12 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 4 |
2 | 19/F | M1 | Non-CR | 46, XX | Intermediate | * | IDA + AraC | - | AraC 2000 mg/m2 on days 1 - 5 | +MIT 12 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 4 |
3 | 81/M | MDS (RA) ⇒ M2 | Non-CR | 46, XY | Intermediate | * | IDA + BHAC | - | AraC 2000 mg/m2 on days 1 - 5 | +MIT 12 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 4 |
4 | 56/F | M1 | Non-CR | Not Available | Not Available | * | IDA + AraC | - | AraC 2000 mg/m2 on days 1 - 5 | +MIT 12 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 7 |
5 | 73/M | M2 | First relapse | 46, XY | Intermediate | 5 | CAG | IDA + AraC, BHAC-DM | AraC 100 mg/m2 on days 1 - 5 | +GO 6 mg/m2 on day 6 | |
6 | 71/M | MDS (RA) ⇒ M2 | First relapse | complex karyotype | Unfavorable | 10 | IDA + AraC | HDAraC + MIT, ×3 | AraC 2000 mg/m2 on days 1-5 | +GO 6 mg/m2 on day 6 | |
7 | 42/M | M0 | First relapse | 46, XY | Intermediate | 19 | IDA + AraC | HDAraC + MIT, ×2 | AraC 2000 mg/m2 on days 1 - 5 | +MIT 12 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 7 |
8 | 67/M | M0 | First relapse | 46, XY | Intermediate | 4 | IDA + AraC | HDAraC + MIT, ×3 | AraC 2000 mg/m2 on days 1 - 5 | +IDA 6 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 7 |
9 | 62/M | Essential thrombocythemia ⇒ M2 | First relapse | 46, XY | Intermediate | 2 | IDA + AraC | HDAraC + MIT, ×1 | AraC 2000 mg/m2 on days 1 - 5 | +MIT 12 mg/m2 on days 1 - 3 | +GO 6 mg/m2 on day 4 |